Ovarian Cancer Canada

Western Regional Blog – BC, YK, AB, NWT and Nunavut

Glutathione for Prevention of Paclitaxel/Carboplatin-Induced Peripheral Neuropathy

Despite evidence supporting the potential benefit of glutathione in the prevention of chemotherapy-induced peripheral neuropathy (CIPN), results of this trial of 185 patients showed no benefit in preventing CIPN as … Continue reading

April 1, 2014

Trends in the Treatment of Chemotherapy-Induced Peripheral Neuropathy

“…chemotherapy-induced neuropathy is a big, big problem; it is one of the more prominent toxicities we have with a number of commonly used chemotherapy agents, such as the platinum agents … Continue reading

March 17, 2014

The Search for Treatments to Reduce Chemotherapy-Induced Peripheral Neuropathy

Deirdre R. Pachman, Charles L. Loprinzi, Axel Grothey, Lauren E. Ta J. Clin. Invest. doi:10.1172/JCI73908. This article Copyright © 2013, The American Society for Clinical Investigation http://www.jci.org/articles/view/73908 Preview Oxaliplatin, a commonly … Continue reading

January 16, 2014

Neuropathic Pain Resulting From Pelvic Masses

“Tumor bulk reduction with appropriate anti-neoplastic therapies. Medication management of pain and concurrent non-pain symptoms. Analgesic medications include antidepressants, anticonvulsants, and opioids. Consideration of symptom management in the context of prognosis, functional goals, … Continue reading

December 12, 2013

Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients with Chemotherapy-Induced Painful Peripheral Neuropathy: A Randomized Clinical Trial

”A study of 231 cancer patients found that the use of duloxetine (Cymbalta) reduced chemotherapy induce peripheral neuropathy. Patients either received Cymbalta or a placebo; in the Cymbalta arm, 59% … Continue reading

May 16, 2013

OCNA’s Report from the Society of Gynecologic Oncology 2013 Annual Meeting

“At this year’s Society of Gynecologic Oncology (SGO) Annual Meeting, numerous presentations and posters explored issues related to ovarian cancer, some of which are summarized below.”   http://www.ovariancancer.org/2013/04/02/report-from-the-society-of-gynecologic-oncology-2013-annual-meeting/ At this year’s … Continue reading

April 20, 2013

Duloxetine Decreased Chemotherapy-Induced Peripheral Neuropathic Pain

Duloxetine significantly reduced pain associated with chemotherapy-induced peripheral neuropathy in patients with cancer.  JAMA 2013 Apr 02;309(13)1359-1367, EM Lavoie Smith, H Pang, C Cirrincione, et al http://www.practiceupdate.com/Explore/JournalScan/?id=3428&elsca1=emc_enews_expert-insight&elsca2=email&elsca3=practiceupdate_onc&elsca4=oncology&elsca5=newsletter Commentary by Lee S. … Continue reading

April 20, 2013

Complementary and Alternative Therapies


Research in BC

The Injustices of Ovarian Cancer

Ovarian Cancer Canada