Ovarian Cancer Canada

Western Regional Blog – BC, YK, AB, NWT and Nunavut

Improving Oncologic Outcomes in Endometrial Cancer

This review discusses the current evidence base and ongoing investigation of novel treatment strategies for women with high-risk localized and metastatic endometrial cancer. 



This review will examine existing results on the postoperative treatment of women with high-risk and advanced stage endometrial cancer. Preliminary data suggests that response to treatment is highly dependent on both grade and stage. It is hoped that this discussion will highlight deficiencies in our collective knowledge base to be addressed in future clinical trials for the benefit of women with endometrial cancer.


  • Existing and planned trials in high risk and advanced stage endometrial cancer have included heterogeneous cohorts.
  • Preliminary evidence exists that response to chemotherapy may be correlated with both stage and grade.
  • Consideration should be given to enrolling stage IV patients into phase I trials at diagnosis given their poor prognosis.


This entry was posted on April 1, 2014 by in Research Updates and tagged .

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