Ovarian Cancer Canada

Western Regional Blog – BC, YK, AB, NWT and Nunavut

Prophylactic bilateral oophorectomy at time of hysterectomy for women at low risk: ACOG revises practice guidelines for ovarian cancer screening in low-risk women

C.A. Larson


The parallels in Ablin’s research on prostate cancer and research conducted on oophorectomy in women at low risk involve overly aggressive screening and treatment, with the number needed to treat (NNT) being of critical importance. The NNT is the number of individuals who must be treated to spare one life from mortality attributable to (in this case) prostate or ovarian cancer. For routine screening in men at low risk for developing prostate cancer, 48 is the NNT, according to Otis Brawley md, chief medical officer of the American Cancer Society5,6. According to Sarah Miles MD, an ovarian conservationist and outcomes researcher interviewed in the dissertation research, the NNT for prophylactic bilateral oophorectomy in women at low risk for developing ovarian cancer is 300.

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