Ovarian Cancer Canada

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Perioperative and Clinical Outcomes in the Management of Epithelial Ovarian Cancer Using a Robotic or Abdominal Approach

In this retrospective analysis comparing robotic-assisted and an open surgical approach for epithelial ovarian cancer, robotic-assisted surgery was associated with a longer surgical time; however, blood loss and hospital stay were reduced. At 1-year follow-up, debulking, survival, and recurrence rates were similar between the two groups. 

Gynecol. Oncol. 2013 Sep 27;[EPub Ahead of Print], GA Feuer, N Lakhi, J Barker, S Salmieri, M Burrell

http://www.practiceupdate.com/journalscan/6222?elsca1=emc_enews_daily-digest&elsca2=email&elsca3=practiceupdate_onc&elsca4=oncology&elsca5=newsletter

ABSTRACT 

Objective: To evaluate the feasibility and efficacy of robotic-assisted management of epithelial ovarian cancer.

Methods: Retrospective review of robotic-assisted or abdominal ovarian cancer cases presenting with pelvic mass, initial staging, or debulking after neoadjuvant chemotherapy performed by a single surgeon (2008–2012). Patient characteristics and outcomes were compared using chi-squared or Student’s t-tests.

Results: There were 63 robotic and 26 abdominal cases. Patient characteristics were similar for age, uterine weight, and BMI, with prior abdominal surgery more common in the abdominal group (p = 0.0257). Robotic operative time was longer (p < 0.0001), while blood loss (p < 0.0001) and hospital stay (p = 0.0009) were reduced. Major complication rates (16% vs. 23%, p = 0.4209) and lymphadenectomy yields (13 vs. 11 nodes, p = 0.2310) were similar. Neoadjuvant chemotherapy was more common in the robotic group (52% vs. 15%, p = 0.0013). Residual disease rates for all cases (73% vs. 50%, p = 0.880) and for Stage II–IV cases (61% vs. 40%, p = 0.929) were equivalent. Follow-up was longer for the abdominal group; however, an equivalent percentage of patients had at least 1 year of follow-up (57% vs. 77%, p = 0.0789). At 1 year, survival and no evidence of disease (NED) rates were equivalent for all cases (survival: 97% vs. 90%, p = 0.2501; NED: 81% vs. 85%, p = 0.6773) and for Stage II–IV cases (survival: 96% vs. 88%, p = 0.3080; NED: 76% vs. 81%, p = 0.6920).

Conclusions: A robotic approach for the management of epithelial ovarian cancer, including patients treated with neoadjuvant chemotherapy, is feasible and effective. Debulking, recurrence, and survival rates were similar to laparotomy at 1 year.

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This entry was posted on November 4, 2013 by in Research Updates and tagged , .

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